Risk factors for chronic postsurgical pain after craniotomy
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.cn131073.20210812.01012
   		
        
        	
        		- VernacularTitle:开颅术后慢性疼痛的危险因素
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Juan WANG
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Liping LI
			        		
			        		;
		        		
		        		
		        		
			        		Jingyi FAN
			        		
			        		;
		        		
		        		
		        		
			        		Wanchen SUN
			        		
			        		;
		        		
		        		
		        		
			        		Yang ZHOU
			        		
			        		;
		        		
		        		
		        		
			        		Ruquan HAN
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 首都医科大学附属北京天坛医院麻醉科 100070
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Craniotomy;
			        		
			        		
			        		
				        		Chronic pain;
			        		
			        		
			        		
				        		Postoperative complications;
			        		
			        		
			        		
				        		Risk factors
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Anesthesiology
	            		
	            		 2021;41(10):1202-1205
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective:To identify the risk factors for chronic postsurgical pain (CPSP) after craniotomy.Methods:This was a single-center retrospective cohort study.The patients who underwent craniotomy in Beijing Tiantan Hospital, Capital Medical University from December 2019 to May 2020 were enrolled.The occurrence of CPSP, anxiety, depression and quality of life were determined by telephone follow-up with Short-form McGill Pain Questionnaire-2, Patient Health Questionnaire-9, Generalized Anxiety Disorder 7-Item, a five-level EuroQol five-dimensional questionnaire.The patients were divided into CPSP group ( n=106) and non-CPSP group ( n=252) according to the results of investigation.Then univariate analysis and logistic regression analysis were performed to identify the risk factors for CPSP. Results:There was significant difference in age, a history of preoperative pain, a history of alcohol addiction, transoccipital approach and degree of lesion resection between the two groups ( P<0.05). The results of logistic regression analysis showed that age ≥ 60 yr was a protective factor for CPSP after craniotomy; a history of preoperative pain ≥3 months, a history of alcohol addiction, transoccipital approach and partial resection of the lesion were independent risk factors for CPSP after craniotomy. Conclusion:Age≥60 yr is a protective factor for CPSP after craniotomy; a history of preoperative pain (≥3 months), a history of alcohol addiction, transoccipital approach and partial resection of the lesion are independent risk factors for CPSP after craniotomy.