Research progress of human derived xenograft models in primary liver cancer
10.3760/cma.j.cn113884-20210407-00129
- VernacularTitle:人源肿瘤异种移植模型在原发性肝癌中的应用研究进展
- Author:
Long YANG
1
;
Tao CUI
;
Wen TONG
;
Yamin ZHANG
Author Information
1. 天津市第一中心医院肝胆外科 南开大学医学院，天津 300384
- Keywords:
Liver neoplasms;
Patient-derived tumor xenograft;
Precise treatment
- From:
Chinese Journal of Hepatobiliary Surgery
2021;27(11):868-871
- CountryChina
- Language:Chinese
-
Abstract:
With the development and marketing of a variety of new anti-tumor drugs, it the patients with liver cancer were benefited but it also raised a series of new problems. How to develop individualized therapeutic plans for the patients with liver cancer has always been bothering the clinicians. Patient-derived xenograft model retains the histological characteristics, molecular diversity and microenficity of human-derived tumors, and it can help conduct in vitro experiments, which can solve the above problems to a certain extent. This article summarizes the research progress of the application of patient-derived xenograft models on the diagnosis and treatment of primary liver cancer.
