A case of the mutation of the poems syndrome with M protein negative in ascites
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.cn101721-20210402-00030
   		
        
        	
        		- VernacularTitle:以腹水为突出表现的M蛋白阴性的POEMS综合征变异型一例
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Jie YANG
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Yongbin YANG
			        		
			        		;
		        		
		        		
		        		
			        		Jie LI
			        		
			        		;
		        		
		        		
		        		
			        		Ruicang WANG
			        		
			        		;
		        		
		        		
		        		
			        		Jun YUAN
			        		
			        		;
		        		
		        		
		        		
			        		Hongling HAO
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 河北省人民医院血液科,石家庄 050000
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		POEMS syndrome;
			        		
			        		
			        		
				        		M protein
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Clinical Medicine of China
	            		
	            		 2021;37(4):368-369
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	POEMS syndrome is a rare clinical disease associated with plasma cell diseases.Classic pentalogy includes: multiple peripheral neuropathy, organ enlargement, endocrine disorders, M-proteinemia and skin lesions.Due to its rarity, multiple system involvement and high clinical heterogeneity, the missed diagnosis rate and misdiagnosis rate are high.This paper reports a case of M protein negative POEMS syndrome with ascites as the prominent manifestation.