Targeted temperature management of severe traumatic brain injury in children

VernacularTitle:儿童严重创伤性脑损伤的目标体温管理
Author: Jingli YAN ¹ ; Wei XU
Author Information

1. 国家儿童区域医疗中心(东北)　中国医科大学附属盛京医院小儿重症监护病房，沈阳　110004
Keywords: Traumatic brain injury; Targeted temperature management; Therapeutic hypothermia; Children
From: Chinese Pediatric Emergency Medicine 2021;28(10):850-854
CountryChina
Language:Chinese
Abstract: Traumatic brain injury(TBI) is one of leading causes of death and disability in children.Targeted temperature management(TTM) may reduce unfavorable outcomes of TBI patients, and many studies have made much effort for developing a norm in managing temperature in TBI patients.TTM, including therapeutic hypothermia, has been recognized as one of candidate methods of neuroprotective treatment.However, the efficacy of hypothermia for patients with severe TBI is not clear.In this article, we will review studies on the potential effects of hypothermia, discuss the possible pathophysiology of neuroprotection with therapeutic hypothermia in PICU, and explore the role of TTM in pediatric severe TBI.