Study progress of exosomes derived from mesenchymal stem cells in the treatment of complications related to preterm infants
10.3760/cma.j.cn101070-20200616-01000
- VernacularTitle:间充质干细胞来源的外泌体治疗早产儿并发症的研究进展
- Author:
Haoming CHEN
1
;
Qingfei HAO
;
Xiuyong CHENG
Author Information
1. 郑州大学第一附属医院新生儿科，郑州 450052
- Keywords:
Exosomes;
Mesenchymal stem cell;
Preterm;
Bronchopulmonary dysplasia;
Brain injury;
Necro-tizing enterocolitis;
Retinopathy of prematurity
- From:
Chinese Journal of Applied Clinical Pediatrics
2021;36(21):1673-1676
- CountryChina
- Language:Chinese
-
Abstract:
Although great progress has been made in perinatal and neonatal medicine, the morbidity and mortality of premature complications remain high.At present, the prevention and treatment of preterm infants with broncho-pulmonary dysplasia, brain injury, necrotizing enterocolitis, retinopathy of prematurity and other complications are cha-llenging.Experimental evidences have shown that regenerative medicine based on mesenchymal stem cells is a promising therapeutic strategy for premature complications, although it has potential risks like tumorigenicity and immune rejection.Exosomes are the key mediators of mesenchymal stem cells, which have been a promising method for the treatment of premature complications.This study aims to review the research progress of exosomes derived from mesenchymal stem cells in the treatment of premature complications.
