Advances in thoracic radiotherapy for extensive stage small cell lung cancer

VernacularTitle:广泛期小细胞肺癌胸部放疗研究进展
Author: Zhi WU ¹ ; Guang YANG ; Lin LI ; Qiang ZHANG
Author Information

1. 山东省禹城市人民医院胸外科　251200
Keywords: Small cell lung carcinoma; Radiotherapy; Extensive stage
From: Journal of International Oncology 2021;48(4):231-234
CountryChina
Language:Chinese
Abstract: Extensive stage small cell lung cancer (ES-SCLC) has a poor prognosis and short survival. Although platinum based combined with etoposide regimens and prophylactic craniocerebral irradiation have become the treatment regimens for ES-SCLC, it still faces the challenges of low local control rate and overall survival rate. As a local treatment, radiotherapy has a wide range of applications, which can not only be used for the radical treatment of local lesions, but also for the selective palliative treatment of advanced patients. Thoracic radiotherapy can improve the local control of ES-SCLC, among them, patients with residual intrathoracic lesions after chemotherapy benefit the most. There is still no unified standard for the appropriate population, optimal dose and segmentation of thoracic radiotherapy, and further research is needed.