Current state of monoamine oxidase A in prostate cancer

VernacularTitle:单胺氧化酶A在前列腺癌中的研究现状
Author: Wei TAN ¹ ; Ye YUAN ; Zili HU
Author Information

1. 重庆医科大学附属第二医院泌尿外科　400010
Keywords: Prostatic neoplasms; Monoamine oxidase A; Neoplasm metastasis
From: International Journal of Surgery 2021;48(6):416-420
CountryChina
Language:Chinese
Abstract: Recent years, the incidence of prostate cancer is increasing, and the need of novel and effective diagnosis and treatment for prostate cancer is becoming more and more urgent.Monoamine oxidase A (MAO-A) is a mitochondrial binding enzyme, which plays an important role in the deamination of some neurotransmitters. Currentlly, some novel studies have shown that MAO-A plays an important role in the occurrence, development and metastasis of prostate cancer. At present, MAO-A has become a potential therapeutic target of prostate cancer and has been widely concerned. This article make a review on the possible mechanism of MAO-A in the occurrence, development and metastasis of prostate cancer and the application of MAO-A in the diagnosis and treatment of prostate cancer.