Progress on the effects of respiratory tract flora on bronchopulmonary dysplasia of premature infants
10.3760/cma.j.issn.1673-4408.2021.10.008
- VernacularTitle:呼吸道菌群对早产儿支气管肺发育不良相关影响的研究进展
- Author:
Anran GUO
1
;
Xiuxiang LIU
Author Information
1. 青岛市妇女儿童医院 NICU 266034
- Keywords:
Premature infants;
Bronchopulmonary dysplasia;
Respiratory flora;
16S rRNA
- From:
International Journal of Pediatrics
2021;48(10):686-688
- CountryChina
- Language:Chinese
-
Abstract:
Bronchopulmonary dysplasia(BPD)is a common chronic lung disease in preterm infants, which seriously affects the survival rate of preterm infants.Its etiology and pathogenesis are complex and unclear.Therefore, the prevention, diagnosis and treatment of BPD have become an important clinical issue.With the rapid development of high-throughput sequencing technology, it has been found that the respiratory tract flora can act as an early biomarker of BPD risk, and then judge the progress of BPD and the timing of treatment, so as to achieve the purpose of early treatment and improved prognosis.This article mainly describes the changes in the diversity and abundance of the respiratory tract flora of BPD in premature infants, the mechanism of action of the flora on BPD, and the future treatment methods based on the flora.
