Progress on detection of exhaled nitric oxide in diagnosis and treatment of asthma in children
10.3760/cma.j.issn.1673-4408.2021.09.005
- VernacularTitle:呼出气一氧化氮检测在儿童哮喘诊治中的研究进展
- Author:
Mengjuan WANG
1
;
Changshan LIU
Author Information
1. 天津医科大学第二医院儿科 天津医科大学儿童呼吸及哮喘研究中心 300211
- Keywords:
Exhaled nitric oxide;
Airway inflammation;
Asthma in children
- From:
International Journal of Pediatrics
2021;48(9):599-604
- CountryChina
- Language:Chinese
-
Abstract:
Asthma is a common chronic airway inflammatory disease in children.In recent decades, the global prevalence of asthma in children has been increasing significantly.As a heterogeneous disease, asthma presents multiple phenotypes, with the type 2(eosinophilic)airway inflammation predominating in children.Currently, fractional exhaled nitric oxide(FeNO)is an internationally recognized marker of eosinophilic airway inflammation, and its value in the diagnosis and treatment of asthma in children has been gradually recognized.This article reviews the sources, detection methods, possible influencing factors of FeNO and its role in the diagnosis and treatment of asthma in children.