Advances on the correlation between hypoxia inducible factor-1α and acute lung injury
10.3760/cma.j.issn.1673-4408.2021.09.003
- VernacularTitle:低氧诱导因子-1α与急性肺损伤相关性的研究进展
- Author:
Youjia WEI
1
;
Chunmei ZHU
Author Information
1. 首都儿科研究所附属儿童医院呼吸科，北京 100020
- Keywords:
Hypoxia inducible factor-1α;
Acute lung injury;
Hypoxia
- From:
International Journal of Pediatrics
2021;48(9):589-592
- CountryChina
- Language:Chinese
-
Abstract:
Acute lung injury is an inflammatory pulmonary disease with complex pathogenesis, frequently resulting in systematic hypoxia.As a central regulator modulating cellular oxygen levels, hypoxia reducible factor-1α affects the development of acute lung injury, which also has been gaining focus as a potential therapeutic target of acute lung injury.Therefore, hypoxia reducible factor-1α is a pivotal factor while understanding the pathogenesis and exploring the therapeutic approach of acute lung injury.
