Progress of histological transformation in indolent lymphoma
10.3760/cma.j.cn115356-20200912-00223
- VernacularTitle:惰性淋巴瘤组织学转化研究进展
- Author:
Cai SUN
1
;
Wei SANG
;
Kailin XU
Author Information
1. 徐州医科大学血液病研究所 徐州医科大学附属医院细胞研究和转化医学中心 徐州医科大学附属医院血液科 221000
- Keywords:
Lymphoma;
Molecular targeted therapy;
Histological transformation
- From:
Journal of Leukemia & Lymphoma
2021;30(11):698-701
- CountryChina
- Language:Chinese
-
Abstract:
Histological transformation is a special histological variation in the progression of indolent lymphoma, and is often accompanied by an aggressive enhanced clinical process. Its poor conventional treatment effect, short survival time and poor prognosis have brought great challenges to the clinical treatment. Except for aggressive clinical manifestations and clear histopathological changes, this transformed type of lymphoma is often accompanied by specific imaging, biological metabolism and molecular genetics variations. This paper reviews the progress of histopathology, clinical characteristics, molecular characteristics and treatment strategy of the histological transformation of indolent lymphoma.
