Advance on Pharmacological Effect and Clinical Application of Danggui Liuhuang Tang
10.13422/j.cnki.syfjx.20202008
- VernacularTitle:当归六黄汤的药理作用和临床应用研究进展
- Author:
Ling YANG
1
;
Jiang-li PENG
1
;
Juan LI
1
;
Yu-ting SU
1
;
Yuan ZHONG
2
;
Shun-xiang LI
1
Author Information
1. School of Pharmacy,Hunan University of Chinese Medicine,Changsha 410208,China
2. Tus-Guhan Group Corporation,Hengyang 421003,China
- Publication Type:Research Article
- Keywords:
Danggui Liuhuang Tang;
pharmacological effect;
clinical application;
advance
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2021;27(2):233-241
- CountryChina
- Language:Chinese
-
Abstract:
Danggui Liuhuang Tang, as one of classical traditional Chinese medicine prescriptions, has been used by major medical experts in clinic since Jin and Yuan dynasties. After review and summarization of relevant literatures on the pharmacological effects and clinical application of Danggui Liuhuang Tang, it was found that Danggui Liuhuang Tang has a wide range of pharmacological activities, and exerts its anti-inflammatory and anti-insulin resistance effects mainly by inhibiting the production of inflammatory factors, such as tumor necrosis factor and interleukin and activating related pathways. In addition, Danggui Liuhuang Tang inhibits the occurrence and development of hepatic fibrosis by attenuating proinflammatory signaling and extracellular matrix accumulation with multiple components, multiple targets, and multiple pathways. Danggui Liuhuang Tang has been widely used in sweat syndromes, with an obvious effect in the treatment of thyroid diseases, diabetes, respiratory tract and other diseases. This paper reviews and summarizes the pharmacological effects and clinical application of Danggui Liuhuang Tang,in an attempt to provide some valuable clues for the subsequent development of Danggui Liuhuang Tang.