Advances in Clinical Application and Hemostatic Mechanism of Charcoal Drugs of Chinese Materia Medica
10.13422/j.cnki.syfjx.20202146
- VernacularTitle:中药炭药的临床应用及止血作用机制研究进展
- Author:
Yu-ting HE
1
;
Qi-meng FAN
1
;
Ji-lian SHI
1
;
Hai-ying LI
1
;
Xue PAN
1
;
Mei-feng XIAO
1
;
Yi-qun ZHOU
1
;
Fu-yuan HE
1
Author Information
1. Laboratory of Supramolecular Mechanism and Mathematic-physics Chracterization for Traditional Chinese Medicine，Hunan Provincial Key Laboratory of Druggability and Preparation Modification for Chinese Materia Medica，College of Pharmacy，Hunan University of Chinese Medicine，Changsha 410208，China
- Publication Type:Research Article
- Keywords:
Chinese materia medica;
charcoal drugs;
hemorrhage;
hemostasis;
processing;
supramolecular Qi chromatography theory;
review
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2021;27(7):201-208
- CountryChina
- Language:Chinese
-
Abstract:
Under the guidance of the theory of traditional Chinese medicine （TCM）， charcoal drugs are widely used in clinical treatment of various bleeding syndromes， in addition， they also have the effect in anti-diarrhea and anti-ulcer， but charcoal drugs are especially effective in stopping bleeding. According to the changes in the properties after processing， the hemostatic effect of charcoal drugs can be roughly divided into two categories. One is not used for hemostasis itself， but used for hemostasis after processing. The other is used for hemostasis itself， and the drug properties are changed or the hemostatic ability is enhanced after processing. By summarizing researches on historical evolution， processing mechanism and pharmacological effects of the commonly used hemostatic charcoal drugs， the author found that preservation or increase of active substances after processing was closely related to the hemostatic effect of charcoal drugs. The hemostatic mechanism mainly involves the influence of coagulation system and platelet function， etc. At the same time， combined with the theory of Qi chromatograph of TCM supramolecular， this paper puts forward the supramolecular research strategy on hemostatic mechanism of charcoal drugs， in order to provide reference for revealing the scientific connotation of charcoal drugs for hemostasis.
