Application Advantages of Nanoemulsion in Field of Traditional Chinese Medicine Preparation：A Review
10.13422/j.cnki.syfjx.20211555
- VernacularTitle:纳米乳在中药制剂领域的应用优势及其研究进展
- Author:
Ling-hui ZOU
1
;
Wen-ya DING
1
;
Qiu-yan HUANG
1
;
Ting-ting LYU
1
;
Ying-gang ZENG
1
;
Jian-fang FENG
1
Author Information
1. School of Pharmacy，Guangxi University of Chinese Medicine， South China Branch of National Engineering Research Center for Manufacturing Technology of Traditional Chinese Medicine Solid Preparation，Nanning 530299，China
- Publication Type:Research Article
- Keywords:
nanoemulsion;
traditional Chinese medicine preparations;
active ingredients;
bioavailability;
targeting technology;
processing technology;
quality evaluation
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2021;27(18):217-226
- CountryChina
- Language:Chinese
-
Abstract:
As a new technology with unique drug delivery advantages， nanoemulsion has been widely used in the field of traditional Chinese medicine （TCM） preparations. By searching， classifying and sorting out the literature reports at home and abroad in recent years， this paper systematically expounded the application advantages and production mechanism of nanoemulsion in delivering effective components of TCM from three aspects of improving oral bioavailability， enhancing targeting effect and delaying drug release. The current formulation optimization strategies， preparation processes and quality evaluation indicators commonly used in TCM nanoemulsion were summarized. Based on the research status of TCM nanoemulsion with different active components， the common problems and possible solutions in the development of TCM nanoemulsion were discussed， and the future research hotspots and directions of TCM nanoemulsion were prospected. This article clarifies the feasibility of nanoemulsion for enriching the selection of TCM dosage forms， which can provide reference for the subsequent rational design and improvement of TCM preparations. At the same time， it is revealed that the research focus of TCM nanoemulsion in the future lies in the integrated research of TCM compounds， and shows a trend of multi-disciplinary joint and targeted research.
