Research Progress on Chemical Constituents， Pharmacological Effect and Clinical Applications of Daturae Flos
10.13422/j.cnki.syfjx.20211549
- VernacularTitle:洋金花的化学成分、药理作用及临床应用研究进展
- Author:
Jin-lian ZHU
1
;
Ying-jia DENG
1
;
Yan-shan HE
1
;
Rui WANG
2
;
Hai-xue KUANG
2
;
Qiu-hong WANG
1
Author Information
1. Guangdong Engineering and Technology Research Center of Standardized Processing of Chinese Materia Medica Decoction Pieces，School of Traditional Chinese Medicine （TCM）， Guangdong Pharmaceutical University，Guangzhou 511400，China
2. Key Laboratory of Basic and Applied Research of Northern Medicine，Ministry of Education，Heilongjiang Key Laboratory of Pharmacodynamic Material Basis of TCM and Natural Medicine，Heilongjiang University of Chinese Medicine，Harbin 150040，China
- Publication Type:Research Article
- Keywords:
Daturae Flos;
withanolides;
terpenoids;
anesthesia;
anti-asthmatic and antitussive;
psoriasis;
anti-inflammatory
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2021;27(23):201-209
- CountryChina
- Language:Chinese
-
Abstract:
Daturae Flos is a traditional antitussive and antiasthmatic medicine， its flowers and leaves are rich in a variety of compounds， including withanolides， alkaloids， terpenes， flavonoids and amides. Because of its antiasthmatic， antitussive， antispasmodic and analgesia effect， it is traditionally used for the treatment of asthma， cough， cold pain in abdominal cavity， rheumatic arthralgia， infantile chronic eclampsia， and can also be used as raw material for surgical anesthesia. Modern pharmacological studies have shown that in addition to the traditional efficacy， Daturae Flos also has anti-inflammatory， immunosuppression， anti-convulsion and other effects， and is often used in the treatment of psoriasis， Parkinson's disease， epilepsy， rheumatoid arthritis and other diseases. At present， the chemical constituents of Daturae Flos are mainly focused on withanolides and alkaloids. At the same time， there is a lack of clear classification of chemical components and the distribution of chemical components in medicinal parts of this medicine， and little information is available for the pharmacological effects of polysaccharides. Based on this， this paper systematically searched relevant literature of Daturae Flos， and summarized and analyzed its chemical composition， pharmacological effect and clinical application， in order to provide reference for further development and utilization of Daturae Flos.
