Clinical Efficacy of Modified Xiao Chengqitang Combined with Acupoint Catgut Implantation in Treating Diet-induced Obesity Syndrome of Stomach Heat Dampness Obstruction
10.13422/j.cnki.syfjx.20210333
- VernacularTitle:加味小承气汤联合穴位埋线治疗食源性肥胖胃热湿阻证的临床疗效
- Author:
De-jun SHANG
1
;
Jian-ming DU
2
;
Qi-jun LIANG
3
;
Qi TAO
4
Author Information
1. Changzhou No.7 People's Hospital，Changzhou 213011，China
2. Wuxi Affiliated Hospital of Nanjing University of Chinese Medicine，Wuxi 214177，China
3. Jiangxi Provincial Hospital of Chinese Medicine，Nanchang 330019，China
4. Jiangsu Province Hospital of Chinese Medicine，Nanjing 210029，China
- Publication Type:Research Article
- Keywords:
diet-induced obesity;
syndrome of stomach heat dampness obstruction;
Xiao Chengqitang;
acupoint catgut implantation;
adipocyte factor
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2021;27(23):131-136
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the clinical efficacy and safety of modified Xiao Chengqitang combined with acupoint catgut implantation in treating diet-induced obesity （DIO） syndrome of stomach heat dampness obstruction. Method:One hundred and seventy-two patients were randomly divided into control group（84 cases） and observation group（88 cases）. Both groups of patients received diet and exercise lifestyle adjustments， and acupoint catgut implantation was performed， 10 days for 1 time， 5 days intervals and then catgut implantation again， for a total of 6 times. Patients in observation group took modified Xiao Chengqitang granular powder， 10 g/time， with lukewarm boiled water in morning and evening. Patients in control group took modified Xiao Chengqitang granular powder simulant， 10 g/time， with lukewarm boiled water， 2 times/day. The treatment courses continued 4 months in two groups. Then the body mass index （BMI）， fat percentage （F%）， obesity， waist to hip ratio （WHR） were measured before and after treatment. Color Doppler ultrasonography was used to measure abdominal fat thickness， prehepatic fat thickness （AHF）， perirenal fat thickness （PRF）， and visceral fat index （UVI）. Fasting blood glucose （FBG）， triglyceride （TG）， total cholesterol （TC）， high-density lipoprotein-cholesterol （HDL-C）， low-density lipoprotein-cholesterol （LDL-C）， fasting insulin （FINS）， leptin （LP）， and adiponectin （APN） were detected before and after treatment， and the homeostasis model assessment of insulin resistance （HOMA-IR） index was calculated. In addition， safety evaluation was also conducted. Result:The BMI， F%， obesity degree and WHR in observation group were all lower than those in control group （P<0.05 or P<0.01）. Subcutaneous fat thickness， AHF， PRF and UVI in observation group were lower than those in control group （P<0.01）. The TG， TC， LDL-C and FINS levels in observation group were lower than those in control group （P<0.01）. The LP and HOMA-IR were also lower than those in control group （P<0.01）， while the APN was higher than that in control group （P<0.01）. The total effective rate in clinical application was （71/80） 88.75% in the observation group， higher than （57/75） 76.00% in the control group （χ2=4.374， P<0.05）. Conclusion:Modified Xiao Chengqitang combined with acupoint catgut implantation in treating DIO syndrome of stomach heat dampness obstruction can adjust LP， APN and other factors， improve energy metabolism such as sugar and fat， and effectively control obesity with high safety， so it is worthy of clinical use.
