Efficacy of Repetitive Transcranial Magnetic Stimulation on Cognitive Dysfunction after Traumatic Brain Injury: A Meta-analysis
10.3969/j.issn.1006-9771.2021.11.007
- VernacularTitle:重复经颅磁刺激治疗脑外伤患者认知障碍的Meta分析
- Author:
Kai-yue HAN
1
;
Hui DANG
1
;
Hao ZHANG
1
Author Information
1. Capital Medical University School of Rehabilitation Medicine, Beijing 100068, China
- Publication Type:Research Article
- Keywords:
repetitive transcranial magnetic stimulation;
traumatic brain injury;
cognitive dysfunction;
meta-analysis
- From:
Chinese Journal of Rehabilitation Theory and Practice
2021;27(11):1282-1290
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the effect of repetitive transcranial magnetic stimulation (rTMS) on cognitive dysfunction after traumatic brain injury (TBI). Methods:Randomized controlled trials (RCTs) of rTMS for treating traumatic brain injury (TBI) patients with cognitive dysfunction were retrieved from the databases of PubMed, Embase, Web of Science, Cochrane Library, CNKI, Wanfang Database, VIP and SinoMed from the establishment of these databases to June, 2021. Two researchers independently screened the articles, extracted the data, and evaluated the quality. Meta-analysis was performed using RevMan 5.4. Results:A total of ten RCTs with 368 patients were included. Subgroup analysis showed that rTMS could improve the single cognitive function (SMD = 1.00, 95%CI 0.04 to 1.96, P = 0.04) but for overall cognitive function (SMD = 0.47, 95%CI -0.05 to 0.98, P = 0.08). rTMS was well tolerated, that the adverse reactions such as dizziness and mild headache were not significantly different from the control group (RR = 1.67, 95%CI 0.98 to 2.86, P = 0.06). Conclusions:It is still uncertain in the effectiveness of rTMS on cognitive dysfunction after TBI, but it is well tolerated.
