Quality Analysis and Suggestion for Ginkgo Folium Tablets and Ginkgo Folium Capsules
10.13422/j.cnki.syfjx.20201750
- VernacularTitle:银杏叶片及银杏叶胶囊的质量分析及建议
- Author:
Li-na LIU
1
;
Hong-yu JIN
1
;
Yao-lei LI
1
;
Wei-yi XU
1
;
Ying WANG
1
;
Ke ZAN
1
;
Shuang-cheng MA
1
Author Information
1. National Institutes for Food and Drug Control，Beijing 100050，China
- Publication Type:Research Article
- Keywords:
Ginkgo Folium tablets;
Ginkgo Folium capsules;
quality evaluation;
terpene lactones;
sophoricoside;
free flavonoids;
flavonol glycosides
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2021;27(1):147-153
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To conduct quality evaluation of Ginkgo Folium preparations by analyzing the national evaluation sampling test results， analyze the quality differences， and put forward suggestions for the improvement of quality standards and market supervision. Method:The contents of total flavonol glycosides and terpene lactones in Ginkgo Folium tablets and Ginkgo Folium capsules were determined according to the methods of determination in the 2015 edition of Chinese Pharmacopoeia （the first volume）， and the contents of free flavonoids （quercetin， kaempferide and isorhamnetin） and sophoricoside in Ginkgo Folium preparations were determined according to related supplementary testing method of Ginkgo Folium tablets and Ginkgo Folium capsules issued by National Medical Products Administration. The quality differences of Ginkgo Folium preparations from different batches and different manufacturers were compared according to the contents of total flavonol glycosides， terpene lactones， free flavonoids and sophoricoside in 328 batches of Ginkgo Folium tablets and Ginkgo Folium capsules manufactured by 48 enterprises. Result:Quality of 328 batches of Ginkgo Folium tablets and Ginkgo Folium capsules was in accordance with the standard， but the contents of terpene lactones and total flavonol glycosides were all distributed in a wide range， and the quality of samples varied greatly among different enterprises. Conclusion:It is recommended that each enterprise should optimize the production process and strictly control the raw materials to ensure the consistency between different batches of samples.
