Considerations on the elevation of aminotransferases in primary biliary cholangitis
10.3969/j.issn.1001-5256.2021.10.005
- VernacularTitle:原发性胆汁性胆管炎合并转氨酶升高的思考
- Author:
Mingli HU
1
;
Qixia WANG
1
;
Xiong MA
1
Author Information
1. Shanghai Institute of Digestive Disease, Division of Gastroenterology and Hepatology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200001, China
- Publication Type:Discussions by experts
- Keywords:
Liver Cirrhosis, Biliary;
Transaminases;
Autoimmune Diseases
- From:
Journal of Clinical Hepatology
2021;37(10):2277-2279
- CountryChina
- Language:Chinese
-
Abstract:
Primary biliary cholangitis (PBC) is an autoimmune-mediated chronic cholestatic liver disease, with the typical biochemical manifestation of significantly elevated alkaline phosphatase (ALP) and gamma-glutamyl transpeptidase (GGT), with or without mild-to-moderate elevation of aminotransferases. ALP and GGT play an important role in the diagnosis and monitoring of PBC. With a deeper understanding of PBC, the significance of elevated aminotransferases in diagnosis and treatment has attracted more and more attention. This article briefly summarizes the significance of elevation of aminotransferases in PBC patients.
