Effectiveness of virtual reality immersion on procedure-related pain and anxiety in outpatient pain clinic: an exploratory randomized controlled trial
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3344/kjp.2021.34.3.304
   		
        
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Young JOO
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Eun-Kyung KIM
			        		
			        		;
		        		
		        		
		        		
			        		Hyun-Gul SONG
			        		
			        		;
		        		
		        		
		        		
			        		Haesun JUNG
			        		
			        		;
		        		
		        		
		        		
			        		Hanssl PARK
			        		
			        		;
		        		
		        		
		        		
			        		Jee Youn MOON
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. Department of Anesthesiology and Pain Medicine, CHA Ilsan Medical Center, CHA University School of Medicine, Goyang, Korea
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Clinical Research Article
 
        	
        	
            
            
            	- From:The Korean Journal of Pain
	            		
	            		 2021;34(3):304-314
	            	
            	
 
            
            
            	- CountryRepublic of Korea
 
            
            
            	- Language:English
 
            
            
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		        	Abstract:
			       	
			       		
				        
				        	Background:The study investigated virtual reality (VR) immersion in alleviating procedure-related pain in patients with chronic pain undergoing fluoroscopy-guided minimally-invasive intervention in a prone position at an outpatient clinic. 
				        	
				        
				        	Methods:In this prospective randomized controlled study, 38 patients undergoing lumbar sympathetic ganglion block were randomized into either the VR or the control group. In the VR group, procedure-related pain was controlled via infiltration of local anesthetics while watching a 30-minute VR hypnotic program. In the control group, the skin infiltration alone was used, with the VR device switched off. The primary endpoint was an 11-point score on the numerical rating scale, indicating procedure-related pain. Patients’ satisfaction with pain control, anxiety levels, the need for additional local anesthetics during the procedure, hemodynamic stability, and any adverse events were assessed. 
				        	
				        
				        	Results:Procedure-related pain was significantly lower in the VR group (3.7 ± 1.4) than in the control group (5.5 ± 1.7; P = 0.002). Post-procedural anxiety was lower in the VR group than in the control group (P = 0.025), with a significant reduction from pre-procedural anxiety (P < 0.001). Although patients’ satisfaction did not differ significantly (P = 0.158) between the groups, a higher number of patients required additional local anesthetics in the control group (n = 13) than in the VR group (n = 4; P = 0.001). No severe adverse events occurred in either group during the study. 
				        	
				        
				        	Conclusions:VR immersion can be safely used as a novel adjunct to reduce procedural pain and anxiety during fluoroscopic pain intervention.