Awareness on expiration date of repackaged prescription medications and pulverization of solid pills: A questionnaire study
	    		
		   		
		   			
		   		
	    	
    	 
    	10.24304/kjcp.2021.31.2.96
   		
        
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		So Yeon KIM
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Yeo Jin CHOI
			        		
			        		;
		        		
		        		
		        		
			        		Hyun Soon SOHN
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. College of Pharmacy, CHA University, Gyeonggi-do 11160, Republic of Korea
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Original Article
 
        	
        	
            
            
            	- From:Korean Journal of Clinical Pharmacy
	            		
	            		 2021;31(2):96-103
	            	
            	
 
            
            
            	- CountryRepublic of Korea
 
            
            
            	- Language:English
 
            
            
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		        	Abstract:
			       	
			       		
				        
				        	Background:The number of elderly people with comorbidities who experience dysphagia associated with geriatric disorders, such as stroke, Parkinson’s disease, and Alzheimer’s dementia, is increasing. Consequently, the demand for long-term prescriptions of powdered medications is expected to rise. Most patients procure repackaged prescription medications from pharmacies; however, the guidelines regarding their expiration dates are unclear. 
				        	
				        
				        	Objectives:The aim of this study was to assess awareness among adults regarding the expiration dates and drug stability issues associated with repackaged prescription medications, including powdered medications. 
				        	
				        
				        	Methods:A questionnaire with 16 components was designed and distributed online (August 1-September 1, 2019) to adults aged 19 years or older. Statistical analyses, including descriptive analysis and chi-square test, were conducted on the obtained data. A p-value <0.05 was considered significant. 
				        	
				        
				        	Results:Data from 254 respondents were analyzed; 191 (75.20%) respondents worked in non-healthcare-related fields. A significant number of healthcare workers recognized the stability issues associated with powdered medications (p<0.001). However, a large proportion of healthcare workers were not aware of the expiration dates (p>0.05). 
				        	
				        
				        	Conclusions:More than half of the total respondents, including healthcare workers, were not familiar with the appropriate expiration dates of repackaged prescription medications. The establishment of evidence-based guidelines regarding drug expiration dates and the dissemination of awareness among patients are required. Furthermore, clinical practices including repackaging or pulverizing medications for long-term prescriptions should be avoided owing to the associated drug stability issues.