Initial Serum Ammonia as a Predictor of Mortality in Patients with Acute Glufosinate Ammonium Herbicide Poisoning
10.22537/jksct.2020.18.2.136
- Author:
Eun Na LAE KO
1
;
Dong Hoon KIM
;
Soo Hoon LEE
;
Jin Hee JEONG
;
Sang Bong LEE
;
Aejin SUNG
;
Ja Hyoen SUH
;
Changwoo KANG
Author Information
1. Department of Emergency Medicine, Gyeongsang National University School of Medicine, Jinju, Korea
- Publication Type:ORIGINAL ARTICLE
- From:Journal of The Korean Society of Clinical Toxicology
2020;18(2):136-140
- CountryRepublic of Korea
- Language:English
-
Abstract:
Purpose:The association of the initial serum ammonia level with in-hospital mortality in patients with acute glufosinate-ammonium herbicide poisoning was studied.
Methods:This retrospective cohort study was conducted between March 2012 and August 2019 in the emergency department after glufosinate-ammonium herbicide poisoning. Survivors and non-survivors were analyzed using a Mann-Whitney U test and Fisher’s exact test. Multivariate logistic regression analysis was performed to determine the independent risk factors for mortality.
Results:One hundred and six patients were enrolled; 11 died, yielding a mortality of 10.4%. The serum bicarbonate level was significantly lower in the non-survival group than the survival group. Age, serum ammonia, blood urea nitrogen, creatinine levels, SOFA score, and APACHE II score were significantly higher in the non-survival group than the survival group. Age, serum ammonia, and creatinine level were independent risk factors for mortality in multivariate logistic regression analysis.
Conclusion:The initial serum ammonia level is associated with mortality in patients with acute glufosinate herbicide poisoning.
