A Case of Overlap Syndrome of Systemic Sclerosis and Cryoglobulinemic Vasculitis With Central Nervous System Involvement
10.4078/jrd.2021.28.4.242
- Author:
Youjin JUNG
1
;
Eunyoung EMILY LEE
;
Jina YEO
;
Mi Hyeon KIM
;
Se Rim CHOI
;
Yeong Wook SONG
Author Information
1. Division of Rheumatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
- Publication Type:Case Report
- From:Journal of Rheumatic Diseases
2021;28(4):242-246
- CountryRepublic of Korea
- Language:English
-
Abstract:
Mixed cryoglobulinemic vasculitis (CV) is occasionally caused by autoimmune diseases including systemic sclerosis. Multiorgan involvement such as skin, kidney, and peripheral nerve involvement is common in mixed CV. However, central nervous system (CNS) involvement is extremely rare. Here, we report a case of overlap syndrome of limited cutaneous systemic sclerosis and mixed cryoglobulinemic vasculitis with CNS involvement. The neurologic deficits and systemic symptoms improved promptly after steroid and cyclophosphamide therapy.
