Association of Cardiovascular Disease Risk and Physical Fitness with Cognitive Impairment in Korean Elderly Women
10.5763/kjsm.2021.39.2.51
- Author:
Inhwan LEE
1
;
Hyunsik KANG
Author Information
1. College of Sport Science, Sungkyunkwan University, Suwon, Korea
- Publication Type:Clinical Article
- From:The Korean Journal of Sports Medicine
2021;39(2):51-59
- CountryRepublic of Korea
- Language:English
-
Abstract:
Purpose:This study aimed to investigate the effect of cardiovascular disease (CVD) risk and physical fitness on cognitive impairment in Korean elderly women.
Methods:In a cross-sectional design, a total of 308 Korean elderly women, aged 60 years or older, participated in this study. Measured parameters included the 10-year Framingham risk score (FRS), physical fitness (i.e., upper and lower body strength and flexibility and endurance), and cognitive performance based on Mini-Mental State Examination for dementia screening. The participants were classified as low (＜ 10%) or intermediate and high (≥ 10%) risk groups based on the 10-year FRS and as unfit (lower 50%) or fit (higher 50%) on a composite z-score of physical fitness. Logistic regression was used to estimate the odd ratios (ORs) and confidence intervals (CIs) of cognitive impairment according to the 10-year FRS and physical fitness-based classification.
Results:The low FRS/unfit and intermediate or high FRS/unfit groups had significantly higher risks of cognitive impairment (OR, 3.714; 95% CI, 1.324– 10.418; p=0.013 and OR, 11.345; 95% CI, 4.810– 26.762; p＜ 0.001, respectively) compared with the low FRS/fit group (OR, 1). In particular, the elevated risk of cognitive impairment remained significant (OR, 3.876; 95% CI, 1.400– 10.726; p=0.009) even after adjustments for covariates such as age, body mass index, education, and physical inactivity.
Conclusion:The current findings suggest that an intervention targeting at both CVD risk reduction and physical fitness promotion is urgent as a preventive and/or therapeutic measure against declines in cognitive function in Korean elderly women.
