Effects of Non-pharmacological Intervention on Depression among Patients with Lung Cancer:A Systematic Review and Meta-Analysis
	    		
		   		
		   			
		   		
	    	
    	 
    	10.5388/aon.2021.21.3.140
   		
        
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Yesol KIM
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Bora KIM
			        		
			        		;
		        		
		        		
		        		
			        		Heejung KIM
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. College of Nursing and Brain Korea 21 FOUR Project, Yonsei University, Seoul, Korea
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Original Article
 
        	
        	
            
            
            	- From:Asian Oncology Nursing
	            		
	            		 2021;21(3):140-154
	            	
            	
 
            
            
            	- CountryRepublic of Korea
 
            
            
            	- Language:English
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Purpose:The purpose of this study was to examine the effects of non-pharmacological interventions (NPIs) on depression among patients with lung cancer. 
				        	
				        
				        	Methods:A systematic review and meta-analysis were conducted focusing on randomized controlled trials (RCTs) and quasi-experimental studies. A literature search was performed through PubMed, EMBASE, CINAHL, PsycINFO, Cochrane Library, and five Korean databases in November 2020. Data were analyzed using the Comprehensive Meta-Analysis Ver. 3.0 and Review Manager Ver. 5.4 programs. 
				        	
				        
				        	Results:A total of 37 studies, including 25 RCTs and 12 quasi-experimental studies, were identified; 27 studies reported data suitable for meta-analysis. In meta-analysis, the overall effect sizes for NPIs of RCTs and quasi-experimental studies were −0.61 (95% confidence interval (CI): −0.90, −0.31) and −0.40 (95% CI: −0.59, −0.21), respectively. Among the types of NPI in RCTs, the effect size of psychological therapy was the largest with −0.68 (95% CI: −1.13, −0.23). In addition, information & communication technology (ICT) had a larger effect size of −0.68 (95% CI: −1.13, −0.23), compared to face-to-face intervention. 
				        	
				        
				        	Conclusion:NPIs may have a significant effect in reducing depressive symptoms in patients with lung cancer. It is suggested that further studies develop and apply structured NPIs considering intervention components such as type and mode of ICT delivery.