The Ca
10.1016/j.apsb.2020.12.003
- Author:
Yani LIU
1
;
Zongtao LIU
2
;
KeWei WANG
1
Author Information
1. Department of Pharmacology, School of Pharmacy, Qingdao University Medical College, Qingdao 266073, China.
2. Department of Clinical Laboratory, Qingdao Third People's Hospital, Qingdao 266041, China.
- Publication Type:Review
- Keywords:
ANO1;
ANO1, anoctamin-1;
ASM, airway smooth muscle;
Ang II, angiotensin II;
BBB, blood–brain barrier;
CAMK, Ca2+/calmodulin-dependent protein kinase;
CF, cystic fibrosis;
CFTR, cystic fibrosis transmembrane conductance regulator;
Ca2+-activated Cl– channels (CaCCs);
CaCCinh-A01;
CaCCs, Ca2+ activated chloride channels;
Cancer;
Cystic fibrosis;
DRG, dorsal root ganglion;
Drug target;
EGFR, epidermal growth factor receptor;
ENaC, epithelial sodium channels;
ER, endoplasmic reticulum;
ESCC, esophageal squamous cell carcinoma;
FRT, fisher rat thyroid;
GI, gastrointestinal;
GIST, gastrointestinal stromal tumor;
GPCR, G-protein coupled receptor;
HNSCC, head and neck squamous cell carcinoma;
HTS, high-throughput screening;
ICC, interstitial cells of Cajal;
IPAH, idiopathic pulmonary arterial hypertension;
MAPK, mitogen-activated protein kinase;
NF-κB, nuclear factor κB;
PAH, pulmonary arterial hypertension;
PAR2, protease activated receptor 2;
PASMC, pulmonary artery smooth muscle cells;
PIP2, phosphatidylinositol 4,5-bisphosphate;
PKD, polycystic kidney disease;
T16Ainh-A01;
TGF-β, transforming growth factor-β;
TMEM16A;
VGCC, voltage gated calcium channel;
VRAC, volume regulated anion channel;
VSMC, vascular smooth muscle cells;
YFP, yellow fluorescent protein
- From:
Acta Pharmaceutica Sinica B
2021;11(6):1412-1433
- CountryChina
- Language:English
-
Abstract:
Anoctamin 1 (
