Wake-Promoting Effect of Bloodletting Puncture at Hand Twelve Jing-Well Points in Acute Stroke Patients: A Multi-center Randomized Controlled Trial.
10.1007/s11655-020-3093-8
- Author:
Nan-Nan YU
1
;
Zhi-Fang XU
2
;
Yang GAO
3
;
Zhi-Liang ZHOU
4
;
Xue ZHAO
2
;
Dan ZHOU
2
;
Zhen-Guo WANG
5
;
Ze-Lin CHEN
2
;
Xing-Fang PAN
6
,
7
;
Yi GUO
7
,
8
Author Information
1. Department of Traditional Chinese Medicine, Xijing Hospital, the Air Force Medical University, Xi'an, 710032, China.
2. Acupuncture Research Center, Tianjin University of traditional Chinese Medicine, Tianjin, 301617, China.
3. Department of Acupuncture and Moxibustion, the First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300193, China.
4. Department of Acupuncture and Moxibustion, the Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300150, China.
5. The Third Department of Encephalopathy, Xi'an Encephalopathy Hospital of Traditional Chinese Medicine, Xi'an, 710032, China.
6. Acupuncture Research Center, Tianjin University of traditional Chinese Medicine, Tianjin, 301617, China. panxingfang@
7. com.
8. Acupuncture Research Center, Tianjin University of traditional Chinese Medicine, Tianjin, 301617, China. guoyi_2016@
- Publication Type:Journal Article
- Keywords:
Glasgow Coma Scale;
Jing-Well point;
acute stroke;
bloodletting;
conscious disturbance;
randomized controlled trial
- From:
Chinese journal of integrative medicine
2021;27(8):570-577
- CountryChina
- Language:English
-
Abstract:
OBJECTIVE:To assess the effect and safety of bloodletting puncture at hand twelve Jing-Well points (HTWPs) in acute stroke patients with conscious disturbance.
METHODS:In this multi-center and randomized controlled trial, 360 patients suffered from ischemic or hemorrhagic stroke with conscious disturbance within 48 h from the onset of symptom were divided into bloodletting (180 cases) and control (180 cases) groups using a block randomization. Patients in both groups received routine Western medicine, and patients in the bloodletting group received additional bloodletting puncture at HTWPs on admission immediately before conventional treatment. The primary outcome measure was Glasgow Coma Scale (GCS) score and the secondary outcomes included blood pressure, respiratory rate and pulse rate. All variables were evaluated at baseline (before bloodletting), 0 (after bloodletting immediately), 15, 30, 50 and 80 min post bloodletting.
RESULTS:At 80 min post bloodletting, the proportion of patients with improved consciousness in the bloodletting group was greater than the control group (P<0.05). In the separate analysis of moderate consciousness disturbance subgroup, bloodletting therapy benefited ischemic patients, and improved the eye and language response of GCS score at 15, 30, 50, 80 min post bloodletting (P<0.05 or P<0.01). No significant differences were observed regarding the secondary outcomes between two groups (P>0.05).
CONCLUSION:The bloodletting puncture at HTWPs was safe and could improve conscious levels of ischemic stroke patients, highlighting a first-aid intervention for acute stroke. (Registration No. ChiCTR-INR-16009530).
