Research progress on chemical constituents, pharmacological activities and clinical application of Bolbostemma paniculatum.
10.19540/j.cnki.cjcmm.20210325.601
- Author:
Han LI
1
;
Kang-Xiong WU
1
;
Kuo-Hao SHI
1
;
Liu TANG
2
;
Cheng-Yuan LIANG
1
Author Information
1. School of Food and Biological Engineering, Shaanxi University of Science & Technology Xi'an 710021, China.
2. New Drug Research Institute, Xi'an Lijun Pharmaceutical Co., Ltd Xi'an 710077, China.
- Publication Type:Journal Article
- Keywords:
Bolbostemma paniculatum;
anti-tumor;
chemical constituent;
clinical application;
pharmacological activity
- MeSH:
Cucurbitaceae;
Drugs, Chinese Herbal/pharmacology*;
Edema;
Triterpenes
- From:
China Journal of Chinese Materia Medica
2021;46(17):4314-4322
- CountryChina
- Language:Chinese
-
Abstract:
Bolbostemma paniculatum is a commonly used Chinese medicinal material effective in clearing heat, removing toxin, eliminating phlegm, and alleviating swelling. The anti-tumor activity it possesses makes it a research hotspot. At present, 76 compounds have been isolated from B. paniculatum, including triterpenoids, sterols, alkaloids, anthraquinones, organic acids, etc., with anti-tumor, antiviral, and immunosuppressive pharmacological activities. This study reviewed the research on the chemical constituents and pharmacological effects of B. paniculatum over the past 20 years, aiming to provide a scientific basis for the research on the pharmacodynamic material basis and promote the development and utilization of B. paniculatum.
