Chemical constituents of sesquiterpenes from Chloranthus multistachys.
10.19540/j.cnki.cjcmm.20210429.204
- Author:
Wei-Ming HUANG
1
;
Fang-You CHEN
1
;
Yu-Ting BIAN
1
;
Yan ZHANG
1
;
Zhi-Chao CHEN
1
;
Peng-Cheng SHUANG
1
;
Yong-Ming LUO
1
Author Information
1. School of Pharmacy, Jiangxi University of Chinese Medicine Nanchang 330004, China.
- Publication Type:Journal Article
- Keywords:
(1R,4R,5R,8S,10R)-chloraeudolide H;
(1S,4S,5S,8R,10S)-chloraeudolide H;
Chloranthus multistachys;
sesquiterpenes
- MeSH:
Chromatography, High Pressure Liquid;
Magnetic Resonance Spectroscopy;
Mass Spectrometry;
Molecular Structure;
Sesquiterpenes;
Stereoisomerism
- From:
China Journal of Chinese Materia Medica
2021;46(16):4145-4149
- CountryChina
- Language:Chinese
-
Abstract:
With repeated silica gel, octadecyl silica(ODS), and Sephadex LH-20 column chromatography, normal-phase and reverse-phase high performance liquid chromatography(HPLC), etc., a pair of new enantiomers and 5 known compounds were separated from the 95% ethanol extract of Chloranthus multistachys. These compounds were identified by the nuclear magnetic resonance spectroscopy(including 1 D-NMR and 2 D-NMR), single-crystal X-ray diffraction, circular dichroism(CD) spectroscopy, mass spectrometry(MS), and some other methods as(1R,4R,5R,8S,10R)-chloraeudolide H(1 a),(1S,4S,5S,8R,10S)-chloraeudolide H(1 b), hydroxyisogermafurenolide(2), 4α-hydroxy-5α,8β(H)-eudesm-7(11)-en-8,12-olide(3), chloraniolide A(4), chlorantene D(5), 4α,8β-dihydroxy-5α(H)-eudesm-7(11)-en-8,12-olide(6). Compounds 1 a and 1 b are a pair of new eudesmane-type sesquiterpene enantiomers, and compounds 2-4 were isolated from C. multistachys for the first time.
