Study on difference of effect of Huoxue drugs and Yiqi Huoxue drugs on tumor metastasis based on immune remodeling.
10.19540/j.cnki.cjcmm.20210223.602
- Author:
Tai-Cheng LU
1
;
Jie LI
2
;
Guang-Hui ZHU
1
;
Jing-Yuan WU
1
;
Jing-Wen YU
1
;
Xiao-Yu ZHU
2
;
Bo-Wen XU
1
;
He-Ping WANG
2
Author Information
1. Guang'anmen Hospital,China Academy of Chinese Medical Sciences Beijing 100053,China Beijing University of Chinese Medicine Beijing 100029,China.
2. Guang'anmen Hospital,China Academy of Chinese Medical Sciences Beijing 100053,China.
- Publication Type:Journal Article
- Keywords:
Huoxue drugs;
Yiqi Huoxue drugs;
immune remodeling;
molecular mechanism;
neoplasms metastasis
- From:
China Journal of Chinese Materia Medica
2021;46(11):2766-2772
- CountryChina
- Language:Chinese
-
Abstract:
Tumor metastasis is an important cause of tumor treatment failure. Its molecular mechanism is closely related to tumor cells remodeling immune cells and immunosuppressive microenvironment, so as to create a suitable soil for tumor cell invasion and growth. "Huoxue Huayu" is one of the important therapeutic principles in cancer treatment, but the influence of Huoxue drugs on tumor metastasis has been controversial in clinical application. In this paper, we systematically summarized the comparative study of Huoxue drugs and Yiqi Huoxue drugs in tumor metastasis in recent years, and discussed the differences of molecular mechanisms of Huoxue drugs and Yiqi Huoxue drugs in anti-tumor metastasis from the perspective of immune remodeling, so as to provide scientific basis for clinical rational application of Huoxue drugs and Yiqi Huoxue drugs.