Endometrial Injury and Preservation after Magnetic Resonance-guided Focused Ultrasound Ablation of Uterine Fibroids.
10.3881/j.issn.1000-503X.13839
- Author:
Jin-Tang YE
1
;
Hai-Feng SHI
2
;
Bai-Yan SU
2
;
Kang ZHOU
2
;
Meng SU
1
;
Yu ZHANG
3
;
Gui-Fang ZHANG
4
;
Zheng-Yu JIN
2
Author Information
1. MR Department,Amcare Women's and Children's Hospital,Beijing 100089,China.
2. Department of Radiology, PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
3. Department of Gynecology and Obstetrics,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
4. Department of Epidemiology,the Key laboratory of Geriatrics,Beijing Institute of Geriatrics, National Center of Gerontology,Beijing Hospital,Beijing 100730,China.
- Publication Type:Journal Article
- Keywords:
endometrial injury;
focused ultrasound;
magnetic resonance;
uterine fibroids
- MeSH:
Child;
Female;
Humans;
Infant;
Leiomyoma;
Magnetic Resonance Imaging;
Magnetic Resonance Spectroscopy;
Retrospective Studies;
Treatment Outcome;
Uterine Neoplasms
- From:
Acta Academiae Medicinae Sinicae
2021;43(3):414-420
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the risk factors for incident endometrial injury and 3-month endometrial injury after magnetic resonance-guided focused ultrasound(MRgFUS)ablation of uterine fibroids(UF). Methods UF patients who were diagnosed in Peking Union Medical College Hospital and underwent MRgFUS ablation in Amcare Women's and Children's Hospital from August 2016 to October 2020 were retrospectively enrolled in this study.Clinical data of 66 UF patients were collected and compared between endometrial injury group and non-injury group.Stepwise regression was employed to determine the risk factors for the incident endometrial injury and 3-month endometrial injury.Multivariate logistic regression analysis was performed to explore the relationship of endometrial injury with age,pre-ablation tumor size,multiple UF,International Federation of Gynecology and Obstetrics(FIGO)classification,T2WI signal intensity,and treatment time.Results In terms of incident endometrial injury,the 66 patients included 41(62.1%)cases with no injury,4 cases(6.1%) with grade 1 injury,5 cases(7.6%)with grade 2 injury,and 16 cases(24.2%)with grade 3 injury.In terms of 3-month endometrial injury,the 66 patients included 49 cases(74.2%)with no injury,5 cases(7.6%)with grade 1 injury,2 cases(3.0%)with grade 2 injury,and 10 cases(15.2%)with grade 3 injury.Stepwise regression analysis indicated that FIGO classification was significantly associated with incident endometrial injury(
