Quantitative Analysis and Validation of Hirsutenone and Muricarpone B from Fermented Alnus sibirica.
	    		
		   		
		   			
		   		
	    	
    	 
    	10.20307/nps.2017.23.2.146
   		
        
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Jun YIN
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Ki Hoon YOON
			        		
			        		;
		        		
		        		
		        		
			        		Seong Hye YOON
			        		
			        		;
		        		
		        		
		        		
			        		Hye Shin AHN
			        		
			        		;
		        		
		        		
		        		
			        		Min Won LEE
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. Laboratory of Pharmacognosy and Natural Product Derived Medicine, College of Pharmacy, Chung-Ang University, Seoul 156-756, South Korea. mwlee@cau.ac.kr
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Original Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Alnus sibirica;
			        		
			        		
			        		
				        		Fermentation;
			        		
			        		
			        		
				        		HPLC;
			        		
			        		
			        		
				        		Validation;
			        		
			        		
			        		
				        		Content
			        		
			        		
	        			
        			
        		
 
        	
            
            	- MeSH:
            	
	        			
	        				
	        				
				        		
					        		Alcoholism;
				        		
			        		
				        		
					        		Alnus*;
				        		
			        		
				        		
					        		China;
				        		
			        		
				        		
					        		Chromatography, High Pressure Liquid;
				        		
			        		
				        		
					        		Fermentation;
				        		
			        		
				        		
					        		Japan;
				        		
			        		
				        		
					        		Korea;
				        		
			        		
				        		
					        		Plants;
				        		
			        		
				        		
					        		Russia;
				        		
			        		
				        		
					        		Tea
				        		
			        		
	        			
	        			
            	
            	
 
            
            
            	- From:Natural Product Sciences
	            		
	            		 2017;23(2):146-150
	            	
            	
 
            
            
            	- CountryRepublic of Korea
 
            
            
            	- Language:English
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Alnus sibirica (AS) geographically distributes in Korea, Japan, Northeast China and Russia. The bark of this plant had been used for antipyretic, expectorant, anti-phlogistic, antitussive, anti-asthmatic and as a health tea for alcoholism. Recently, we studied various biological activities of AS and the isolated diarylheptanoid. In present study, we conducted fermentation of AS (FAS) and isolated two diarylheptanoid (hirsutenone and muricarpone B). Moreover, we established the validation and contents determinations of the two compounds by HPLC on FAS.