Analysis of disease progression and influencing factors of HIV-infected persons in 2010-2020
10.3969/j.issn.1006-2483.2021.04.020
- VernacularTitle:2010—2020年HIV感染者疾病进程及影响因素分析
- Author:
Ling ZHANG
1
;
Changfeng LIN
1
;
Xia SUN
1
;
Xi WEN
1
;
Shijing FU
1
Author Information
1. Department of Infection, Hainan Provincial Third People's Hospital, Haikou 572000 , China
- Publication Type:Journal Article
- Keywords:
HIV;
Incubation period;
Progression
- From:
Journal of Public Health and Preventive Medicine
2021;32(4):88-91
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the disease progression and influencing factors of human immunodeficiency virus (HIV)-infected persons in Sanya area from 2010-2020. Methods Data of HIV infected cases reported in XX region from January 2014 to January 2020 were collected through the National AIDS Comprehensive Prevention and Control Information System. The incidence of AIDS was calculated by the life expectancy method, and the single factors influencing the progression of HIV infection were analyzed from the aspects of sex, age, BMI, nationality, marital status, educational level, highly active anti-retroviral therapy (HAART), anemia, route of transmission, CD4+ cell count, and co-infection of other viruses. Results A total of 761 HIV-infected cases were reported in Sanya areaFrom January 2010 to January 2020, of which 103 had progressed to AIDS (13.53%), the incidence of AIDS was 6.01/100 person-years, the average incubation period was 4.63 years; There were 31 death cases, and the all-cause mortality rate was 1.81/100 person years; Gender, age, HAART treatment status, anemia, CD4+ cell count, and other viral infections were single factors that affect the disease progression of HIV-infected persons (χ2=16.803, 13.362, 15.954, 20.119, 16.039, 15.711, P<0.05), meanwhile, age, HAART treatment status, anemia, CD4+ cell count, and other viral infections were independent risk factors that affect the disease progression of HIV-infected persons (P=0.014, 0.007, 0.017, 0.009, 0.001, 0.001). Conclusion The incubation period is an important stage of the disease progression of HIV-infected patients, moreover, age, HAART treatment status, anemia, CD4+ cell count, and other viral infections are all independent risk factors that affect the disease progression of HIV-infected patients.
