Research progress on immunological mechanisms of radiation-induced brain injury
10.3760/cma.j.cn113030-20200602-00290
- VernacularTitle:放射性脑损伤免疫相关机制研究现状
- Author:
Min FU
;
Xiaoyu LI
;
Na LUO
;
Wenjun ZHU
;
Guangyuan HU
- From:
Chinese Journal of Radiation Oncology
2021;30(3):301-304
- CountryChina
- Language:Chinese
-
Abstract:
Radiation-induced brain injury is a neurological injury caused by radiation therapy of head and neck tumors. The pathogenesis is still unclear. It is hypothesized that immune cells play an important role in radiation-induced brain injury. The excessive activation of microglia in the central nervous system and the migration of peripheral immune cells into the brain collectively promote the incidence and development of radiation-induced brain injury. In this article, the immunological mechanism underlying the radiation-induced brain injury was reviewed.
