Enrichment methods and clinical application of circulating tumor cells
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.cn371439-20200629-00033
   		
        
        	
        		- VernacularTitle:循环肿瘤细胞的富集方法与临床应用
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Dawei NING
			        		
			        		;
		        		
		        		
		        		
			        		Yang OU
			        		
			        		;
		        		
		        		
		        		
			        		Kai CUI
			        		
			        		;
		        		
		        		
		        		
			        		Sheng LI
			        		
			        		;
		        		
		        		
		        		
			        		Dehai GAO
			        		
			        		
		        		
		        		
		        		
		        		
		        		
			        		
			        		
		        		
	        		
        		 
        	
        	
        	
        	
            
            
            	- From:
	            		
	            			Journal of International Oncology
	            		
	            		 2021;48(3):167-171
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	As an emerging tumor marker, the rarity and heterogeneity of circulating tumor cells (CTCs) increase the difficulty of detection. In recent years, CTCs enrichment technology based on biophysical, biochemical and microfluidic properties has been continuously developed, which has promoted the research and application of CTCs in malignant tumors diagnosis, clinical treatment and prognosis evaluation. Although there are still some deficiencies in the detection of CTCs, with the interdisciplinary integration, CTCs will play increasingly important roles in the diagnosis and treatment of malignant tumors.