Mesenchymal stem cells in therapy of coronavirus disease 2019 - a review.
- Author:
Xiaodong SHI
1
;
Lijia YU
1
;
Chunguang DING
1
Author Information
- Publication Type:Review
- Keywords: Coronavirus disease 2019 (COVID-19); clinical research; immune regulation; mesenchymal stem cells; tissue repair and regeneration
- MeSH: Betacoronavirus; COVID-19; China; Coronavirus Infections/therapy*; Humans; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells/cytology*; Pandemics; Pneumonia, Viral/therapy*; SARS-CoV-2
- From: Chinese Journal of Biotechnology 2020;36(10):1979-1991
- CountryChina
- Language:Chinese
- Abstract: Coronavirus disease 2019 (COVID-19) has spread widely on a large scale in the whole world at present, seriously endangering human health. There are still no effective and specific drugs, so it is urgent to find safe and effective therapeutic methods. Mesenchymal stem cells (MSCs) have many biological functions of powerful immunomodulation and tissue repair and regeneration. As a stem cell therapy, it has the potential to reduce the tissue injury and mortality in severe patients infected with novel coronavirus. At present, many research institutions in China and abroad have started a number of clinical research projects about MSCs in the treatment of COVID-19. In addition, those projects have initially confirmed the safety and effectiveness of this therapy. Therefore, this research field has been proved to have a very good clinical therapy prospect.
