Disparity of human immunodeficiency virus incidence and drug resistance in college student, non-student youth and older men who have sex with men: a cross-sectional study from seven major cities of China.
10.1097/CM9.0000000000001161
- VernacularTitle:Disparity of human immunodeficiency virus incidence and drug resistance in college student, non-student youth and older men who have sex with men: a cross-sectional study from seven major cities of China
- Author:
Jing ZHANG
1
;
Jun-Jie XU
1
;
Zhen-Xing CHU
1
;
Qing-Hai HU
1
;
Xiao-Xu HAN
1
;
Bin ZHAO
1
;
Yong-Jun JIANG
1
;
Wen-Qing GENG
1
;
Hong SHANG
1
Author Information
1. NHC Key Laboratory of AIDS Immunology (China Medical University), National Clinical Research Center for Laboratory Medicine, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, China.
- Publication Type:Multicenter Study
- MeSH:
Adolescent;
Adult;
Aged;
China/epidemiology*;
Cities;
Cross-Sectional Studies;
Drug Resistance;
HIV Infections/epidemiology*;
Homosexuality, Male;
Humans;
Incidence;
Male;
Prevalence;
Risk Factors;
Sexual Behavior;
Sexual and Gender Minorities;
Students;
Young Adult
- From:
Chinese Medical Journal
2020;133(23):2778-2786
- CountryChina
- Language:English
-
Abstract:
BACKGROUND:Human immunodeficiency virus (HIV) prevalence among student men who have sex with men (MSM) in college is more than 5.0% and keeps on increasing in China. This study aims to clarify the proportion of HIV recent infection, its propeller and the source among college student MSM.
METHODS:We conducted a multicenter cross-sectional study in seven major Chinese cities during 2012-2013. HIV recent infections (≤ 168 days) and incidence was measured and estimated by BED HIV-1 capture enzyme immunoassay (BED-CEIA) testing strategy. HIV-related behaviors and transmitted drug resistance (TDR) were investigated and compared between the college student MSM, <25-year-old non-student youth MSM (NSYM), and ≥25-year-old non-student non-youth MSM (NSNYM), using structured survey, and analyses of drug resistance.
RESULTS:Overall, 4,496 (4496/4526, 99.3%) were eligible for enrollment, comprising 565 college student MSM, 1,094 NSYM, and 2,837 NSNYM. The proportion of HIV recent infection were 70.3% (26/37), 50.8% (65/128) and 35.1% (95/271), the HIV incidence rate were 10.0 (95% CI: 6.2-13.9)/100PY, 12.9 (95% CI: 9.8-16.1)/100PY, 6.8 (95% CI: 5.4-8.2)/100PY, and TDR prevalence were 7.4% (2/27), 2.0%, (2/98) and 4.9% (11/226), among student MSM, NSYM, and NSNYM, respectively. Among HIV positive student MSM with age< 21-year-old, the proportion of HIV recent infection is 90.9% (10/11). Factors independently associated with HIV recent infection in student MSM was usage of recreational drug in the past 6 months (AOR: 2.5; 95% CI: 1.0-5.8).
CONCLUSIONS:College student MSM had higher proportion of HIV recent infection and TDR than the youth and older MSM in China during 2012-2013. The HIV infections were more likely to happen during the early year of college life among student MSM.
