Surgical treatment and mid-term results of functional single ventricle associated with total anomalous pulmonary venous connection
- VernacularTitle:功能性单心室合并完全型肺静脉异位引流的外科治疗和中期随访结果
- Author:
Bin LI
1
;
Aijun LIU
1
;
Rui SI
1
;
Ming YANG
1
;
Xiangming FAN
1
;
Junwu SU
1
Author Information
1. Department of Pediatric Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, P.R.China
- Publication Type:Journal Article
- Keywords:
Single ventricle;
total anomalous pulmonary venous connection;
congenital heart disease;
surgery
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2021;28(03):344-348
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the mid-term results of surgical treatment for functional single ventricle associated with total anomalous pulmonary venous connection. Methods We reviewed the clinical data and follow-up results of 12 patients in our hospital who underwent both single ventricle series palliation and total anomalous pulmonary venous connection correction from 2008 to 2018. There were 6 males and 6 females at age of 2.3 (1-21) years. Univariable and multivariable Cox proportional hazard regression methods were performed. The Kaplan-Meier method was used to estimate the survival rate. Results All patients were successfully removed from extracorporeal circulation. The cardiopulmonary bypass time was 113.8±42.5 min. The myocardial block time was 57.7±31.7 min. There were 3 in-hospital deaths and 4 late deaths. The causes of death in hospital were pulmonary hypertension, pulmonary hemorrhage, and hypoxemia. During follow-up, the cause of death was heart failure. The survival rate at 1 year and 3 years was 58.3%(95%CI 27% to 80%) and 40% (95%CI 13% to 65%), respectively. Median follow-up was 48.3 months (range: 1 to 118 months). Conclusion Functional single ventricle combined with complete pulmonary venous drainage is a serious clinical disease, with poor therapeutic effect and high overall mortality.
