Combined intraoral and cutaneous using of long pulsed 1064 nm and 2940 nm lasers in facial rejuvenation: a prospective study of two consecutive patients
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.issn.1671-0290.2020.05.003
   		
        
        	
        		- VernacularTitle:长脉宽1064 nm Nd∶YAG与2940 nm Er∶YAG激光联合口内和皮肤治疗改善鼻唇沟皱纹的效果
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Yaqing MO
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Xiaodong DING
			        		
			        		;
		        		
		        		
		        		
			        		Yanfang DANG
			        		
			        		;
		        		
		        		
		        		
			        		Pei LIU
			        		
			        		;
		        		
		        		
		        		
			        		Xuehua LIAO
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 上海时光整形外科医院皮肤科 200010
			        		
		        		
	        		
        		 
        	
        	
        	
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Medical Aesthetics and Cosmetology
	            		
	            		 2020;26(5):368-371
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
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		        	Abstract:
			       	
			       		
				        
				        	Objective:To study the effectiveness and safety of combined intraoral and cutaneous using of long pulsed 1064 nm Nd∶YAG and 2940 nm Er∶YAG lasers in facial rejuvenation.Methods:Twenty-one female patients with different grades of nasolabial fold were treated with 6 sessions of the combination lasers therapy once a month. Standardized photographs of VISIA were taken before and after treatment to record any changes of facial contour and nasolabial folds. The efficacy assessment was judged by two non-group experienced dermatologists using modified Fitzpatrick Wrinkle Scale (MFWS), based on the VISIA photos at base line, twelve-week and six-month after treatment. Self-scoring of 5-level satisfaction from patients was also collected and analyzed. Any side effects and complications were recorded.Results:At 12 weeks, mild and moderate nasolabial folds were improved notably, the mean value of MFWS decreased from 1.59 to 0.90, whereas severe nasolabial folds had no remarkable improvement. Six-month after treatment, 18 patients had notable improved, among them: five out of 7 mild cases, 9 out of 10 moderate cases and 2 out of 4 severe cases, and the mean value of MFWS significantly decreased to 0.57 ( P<0.001). The general satisfactory rate of self-scoring was 86%. Two patients had tolerable light burning pain during treatment and two patients got temporary pigmentation that vanished in three months. There were no other adverse reactions and complications. Conclusion:Combined intraoral and cutaneous using oflong pulse 1064 nm Nd∶YAG laser and 2940 nm Er∶YAG laser is a safe and effective therapy for facial rejuvenation.