Effect of botulinum toxin A on improving the aesthetics of lips
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.issn.1671-0290.2020.05.002
   		
        
        	
        		- VernacularTitle:口周注射A型肉毒毒素丰唇的效果
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Zehao NIU
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Jun SHU
			        		
			        		;
		        		
		        		
		        		
			        		Tian MA
			        		
			        		;
		        		
		        		
		        		
			        		Zhiqiang ZHOU
			        		
			        		;
		        		
		        		
		        		
			        		Guoqing ZHAO
			        		
			        		;
		        		
		        		
		        		
			        		Zhongyou YANG
			        		
			        		;
		        		
		        		
		        		
			        		Ran TAO
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 解放军总医院第一医学中心整形修复科,北京 100853
			        		
		        		
	        		
        		 
        	
        	
        	
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Medical Aesthetics and Cosmetology
	            		
	            		 2020;26(5):364-367
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
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		        	Abstract:
			       	
			       		
				        
				        	Objective:To observe the clinical efficiency, duration of action and adverse reactions of lip contour after local injection of type A botulinum toxin into the orbicularis oculi muscle.Methods:From March 2019 to June 2019, a total of 11 patients (6 males and 5 females, mean age 42.2 years) received superficial injection of botulinum toxin A in the orbicular muscle in our hospital. The change of lip thickness was assessed by Medicis lip fullness scale (MLFS) and the 3D structured light camera was used to collect and analyze the facial data. Pre- and post-treatment effects, duration of action and complications were evaluated.Results:Improvement of upper lip thickness was noted in 11 cases (100%). The average onset time after injection was 14.6 days and average effect maintenance time was 124.1 days. The height of the red lips ( Z=-2.940, P<0.05), the distance from the upper lip to the Ricketts line ( Z=-2.137, P<0.05) and nasolabial angle ( Z=-2.137, P<0.05) were significantly changed one month after the injection. No allergic reaction was observed, and the adverse reactions were mild and reversible. Conclusion:Local injection of botulinum toxin type A can achieve mild lip augmentation.