Research advances of hypertriglyceridemia acute pancreatitis
10.3760/cma.j.issn.1009-9158.2020.03.026
- VernacularTitle:高甘油三酯血症性急性胰腺炎的研究进展
- Author:
Guotao LU
1
;
Mei WEI
;
Weiqin LI
Author Information
1. 南京大学医学院附属金陵医院(东部战区总医院)普通外科,全军普通外科研究所重症胰腺炎中心,南京 210002
- From:
Chinese Journal of Laboratory Medicine
2020;43(3):336-340
- CountryChina
- Language:Chinese
-
Abstract:
In recent years,with the change of lifestyle in China, hypertriglyceridemia (HTG) has been the second leading cause of acute pancreatitis (AP). Recent studies have shown that HTG has long-lasting influences on AP onset (including recurrence), AP severity, as well as pancreatic regeneration. However, the underlying mechanisms of HTG-AP is still unclear, mainly focusing on free fatty acid, microcirculation disturbance, calcium overload, oxidative stress, gene polymorphism and so on. However, there is lack of effective intervention for the diagnosis and treatment of HTG-AP, which needs further study.