Standardization of aldosterone and harmonization of renin in China
10.3760/cma.j.issn.1009-9158.2020.03.010
- VernacularTitle:加强我国醛固酮标准化和肾素一致化建设
- Author:
Weiyan ZHOU
1
;
Chuanbao ZHANG
;
Wenjun MA
;
Jun CAI
;
Wenxiang CHEN
Author Information
1. 北京医院 国家老年医学中心 国家卫生健康委临床检验中心 北京市临床检验工程技术研究中心 中国医学科学院老年医学研究院，北京 100730
- From:
Chinese Journal of Laboratory Medicine
2020;43(3):245-249
- CountryChina
- Language:Chinese
-
Abstract:
Aldosterone and renin are important clinical indicators in the diagnosis and treatment of hypertension. There are two kinds of methods for aldosterone detection, including immunoassay and mass spectrometry. The coefficients of variation within the methods, as well as the deviation between methods are large.And the results of immunoassay are much higher than that of mass spectrometry. Clinically, renin tests mainly include renin concentration and renin activity, both of which have advantages and disadvantages in the diagnosis and treatment of hypertension. The disordered test results of aldosterone and renin brings great trouble to the clinical diagnosis and treatment. Standardization/consistency is urgently needed to make the test results of each laboratory more accurate and comparable. The standardization project for renin and aldosterone in China will greatly promote the standardization process in order to provide accurate and comparable clinical tests.
