The association between the thin-section computed tomography parameters and the invasion and histological subtypes of subsolid nodules measuring 1-2 centimeters in diameter as lung adenocarcinoma: a retrospective study from one single center
10.3760/cma.j.cn112434-20200727-00348
- VernacularTitle:薄层CT参数与1～2 cm亚实性结节肺腺癌浸润程度及组织学亚型相关性分析：单中心回顾性研究
- Author:
Dong LIN
1
;
Yangli YU
;
Xiaosang CHEN
;
Shuai WANG
;
Songtao XU
;
Yu LIU
;
Cheng QIAN
;
Hong FAN
;
Di GE
;
Qun WANG
;
Lijie TAN
Author Information
1. 复旦大学附属中山医院胸外科，上海 200032
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2020;36(9):549-552
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the association between the parameters of thin-section computed tomography and the invasion and histological subtypes of subsolid nodules measuring 1-2 centimeters in diameter as lung adenocarcinoma.Methods:We retrospectively reviewed the cases with subsolid nodules measuring 1-2 centimeters on thin-section computed tomography and histologically confirmed as lung adenocarcinoma.Results:A total of 135 patients were enrolled in this study, including 23 with pure ground glass nodules and 112 with part-solid ground glass nodule. We observed significant differences of nodule size, solid component size, consolidation-to-tumor ratio, nodule attenuation and attenuation ratio( P<0.0001). The receiver operating curve indicated certain predictive value of solid component size, nodule attenuation and attenuation ratio: AUC were 0.838(0.756-0.919)、0.823(0.729-0.917) and 0.820(0.726-0.914), respectively. Of the invasive adenocarcinoma, those with solid or micropapillary components merely showed a significance in solid component size( P=0.024). Conclusion:The parameters of thin-section computed tomography of 1-2 centimeters subsolid nodules showed significant differences in varied invasiveness of lung adenocarcinoma, and these could have certain predictive value.
