Endoscopic submucosal dissection for superficial hypopharyngeal carcinomas (with video)
10.3760/cma.j.cn321463-20191203-00599
- VernacularTitle:内镜黏膜下剥离术治疗下咽早期癌及癌前病变的临床价值（含视频）
- Author:
Rui ZHAO
1
;
Yu BAO
;
Lingxiao ZHOU
;
Zhenming ZHANG
;
Wusong LIU
;
Jie HUANG
Author Information
1. 四川省肿瘤医院 电子科技大学医学院附属肿瘤医院内镜诊治部，成都 610041
- From:
Chinese Journal of Digestive Endoscopy
2020;37(7):495-498
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the efficacy and safety of endoscopic submucosal dissection(ESD) for early hypopharyngeal carcinoma and precancerous lesions.Methods:Data of 23 patients with early hypopharyngeal carcinoma and precancerous lesions who underwent ESD in Sichuan Cancer Hospital from December 2015 to May 2019 were analyzed.Results:A total of 23 patients with 30 lesions were enrolled in the study. All patients were male, with mean age of 60.3 years (ranged 47-72). Of the 23 patients, 13 had synchronous esophageal cancer, 3 had metachronous esophageal cancer, and 7 high-grade intraepithelial neoplasia(HGIN) of the esophagus. The mean procedure time was 74 minutes. The en bloc resection rate was 100%. Pathological results revealed that 21 lesions were HGIN, 8 lesions were intramucosal carcinoma and 1 lesion had tumor invasion of the submucosa. Two patients had positive horizontal margin and 1 patient had positive vertical margin. The curative resection rate was 90%. No bleeding, perforation or dyspnea occurred during or after ESD.Conclusions:ESD is safe and effective for early hypopharyngeal cancer and precancerous lesions.
