Progress in use of metformin in pregnancy with diabetes
10.3760/cma.j.issn.1007-9408.2020.02.009
- VernacularTitle:二甲双胍在妊娠期应用的研究进展
- Author:
Ye FENG
1
;
Huixia YANG
Author Information
1. 北京大学第一医院妇产科妊娠合并糖尿病母胎医学北京市重点实验室 100034
- Keywords:
Metformin;
Diabetes,gestational;
Validation studies;
Clinical protocols
- From:
Chinese Journal of Perinatal Medicine
2020;23(2):121-125
- CountryChina
- Language:Chinese
-
Abstract:
The efficacy as well as short-and long-term safety of metformin in women with gestational diabetes mellitus have been constantly confirmed in recent years.Metformin could decrease the weight gain during pregnancy and the incidence of hypoglycemia compared with insulin,without increasing the incidence of adverse pregnant outcomes.Moreover,no significant adverse outcome has been found in the offspring of women treated with metformin in pregnancy.This article reviews the evidence for efficacy and safety of using metformin during pregnancy,summarizes the latest guidelines and recommendations,and describes the specific medication regimen.
