Anti-leucine-rich glioma-inactivated protein 1 and glutamic acid decarboxylase 65 antibodies double-positive autoimmune encephalitis complicated with vitiligo: a case report
10.3760/cma.j.cn113694-20200330-00218
- VernacularTitle:抗富亮氨酸胶质瘤失活蛋白1、谷氨酸脱羧酶65抗体双重阳性自身免疫性脑炎并白癜风一例
- Author:
Xuemei FAN
1
;
Songyan LIU
;
Limin HUANG
;
Yafei ZHU
;
Qing ZHENG
;
Xianhui HUANG
;
Jie WANG
Author Information
1. 吉林大学中日联谊医院神经内科, 长春 130033
- From:
Chinese Journal of Neurology
2020;53(10):810-813
- CountryChina
- Language:Chinese
-
Abstract:
Autoimmune encephalitis (AE) refers to a kind of encephalitis mediated by immune mechanism, which is one of adult symptomatic epilepsy due to unknown etiology. Early recognition has certain difficulty. AE patients with multiple antineuronal antibody co-existing are relatively rare. Clinical symptoms are more complex and variable, and can involve a wider range of immune system. A case of temporal lobe epilepsy with anti-leucine-rich glioma-inactivated protein 1 and glutamic acid decarboxylase 65 antibodies double-positive AE complicated by vitiligo and diabetes is reported. After immune shock and continuous immunotherapy, the patient completely recovered from encephalitis and diabetes, and vitiligo was improved obviously.
