Anti-Yo-associated paraneoplastic cerebellar degeneration in a man with gastric adenocarcinoma: one case report and literature review
10.3760/cma.j.cn113694-20190827-00532
- VernacularTitle:罕见并发于胃癌的抗Yo抗体阳性副肿瘤性小脑变性一例并文献复习
- Author:
Yanfei LI
1
;
Yaling LIU
;
Yanjie JIA
;
Shujie JIAO
Author Information
1. 郑州大学第一附属医院神经内科 450001
- From:
Chinese Journal of Neurology
2020;53(5):368-371
- CountryChina
- Language:Chinese
-
Abstract:
A male patient of acute onset is reported, whose main clinical manifestations were ataxia and dysarthria, with elevated carcinoembryonic antigen, non-small cell lung cancer antigen, carbohydrate antigen 72-4, positive anti-Yo antibody. The patient′s gastroscopy and biopsy result suggested gastric cancer, and his symptoms got better after radical surgery. Anti-Yo-associated paraneoplastic cerebellar degeneration complicated with gastric adenocarcinoma was diagnosed. If encountering cases of ataxia or dysarthria in clinical work, the possibility of paraneoplastic cerebellar degeneration should be considered and evidence for tumor should be searched, so as to avoid missed diagnosis or misdiagnosis.
