How much vitamin D is needed to maintain bone health?
10.3760/cma.j.cn311282-20200218-00079
- VernacularTitle:究竟需要补充多少维生素D才能维持骨骼健康？
- Author:
Zhongjian XIE
1
Author Information
1. 中南大学湘雅二医院代谢内分泌科，中南大学代谢内分泌研究所，湖南省代谢性骨病重点实验室，国家代谢性疾病临床医学研究中心，长沙 410011
- From:
Chinese Journal of Endocrinology and Metabolism
2020;36(10):828-831
- CountryChina
- Language:Chinese
-
Abstract:
Vitamin D is the precursor of 1, 25-dihydroxyvitamin D, which is considered as the critical hormone involved in the regulation of calcium and phosphate homeostasis and bone metabolism. Adequate vitamin D status is very important in the maintenance of bone health. However, recent controlled vitamin D intervention studies showed controversial results. One of the important reasons for this is the difference in the baseline of vitamin D status among studies. The vitamin D status in the Chinese population is much lower as compared to that in Western countries. Postmenopausal women and elderly with vitamin D deficiency should take appropriate vitamin D supplementation in order to achieve serum 25-hydroxyvitamin D levels greater than 20 ng/ml or even 30 ng/ml. However, it may be difficult to bring more benefits from excessive supplementation in order to maintain bone health.
