Research progress on chronic obstructive pulmonary disease and mechanisms underlying its regulation of aging
10.3760/cma.j.issn.0254-9026.2020.02.027
- VernacularTitle:慢性阻塞性肺疾病与衰老调控机制的研究进展
- Author:
Kaixiu CAO
1
;
Zheng LI
;
Xianmin WANG
Author Information
1. 新疆医科大学第四临床医学院，乌鲁木齐 830000
- From:
Chinese Journal of Geriatrics
2020;39(2):241-244
- CountryChina
- Language:Chinese
-
Abstract:
Chronic obstructive pulmonary disease(COPD)is a common respiratory disease with a high disability and mortality rate, and it has become one of the major public health issues of concern worldwide.It includes small airway disease and emphysema caused by abnormal tissue repair, but its pathogenesis is still unclear.COPD is currently viewed as a disease of accelerated lung aging and is closely associated with aging mechanisms such as telomere/telomerase, epigenetic changes and mitochondrial dysfunction.This article reviews research progress on the mechanisms linking COPD and aging-related regulation.
