Research on non-culture-based method in diagnosis of invasive candidiasis
10.3760/cma.j.issn.1674-2397.2020.02.013
- VernacularTitle:基于非培养法诊断侵袭性念珠菌病的研究现状
- Author:
Yingzhu CHEN
1
;
Yun XIA
Author Information
1. 重庆医科大学附属第一医院检验科 400016
- From:
Chinese Journal of Clinical Infectious Diseases
2020;13(2):149-153
- CountryChina
- Language:Chinese
-
Abstract:
Invasive candidiasis (IC) is lack of specific clinical symptoms and signs. Conventional microbiological culture for IC diagnosis presents poor sensitivity and time-consuming. Non-culture-based methods include the detection of candida carbohydrates (1, 3-β-D-glucan, mannan/anti-mannan), candida protein and candida nucleic (PCR, T2Candida). Because they are sensitive and less time-consumming, the method have been widely used for IC diagnosis. This article describes the clinical application and limitations of these non-culture methods in the diagnosis of candida diseases, to provide reference for the clinical use.
